Trout, Bernhardt : rechercher sur Z-Library

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1

Application of Continuous Crystallization in an Integrated Continuous Pharmaceutical Pilot Plant

Zhang, Haitao, Lakerveld, Richard, Heider, Patrick L., Tao, Mengying, Su, Min, Testa, Christopher J., D’Antonio, Alyssa N., Barton, Paul I., Braatz, Richard D., Trout, Bernhardt L., Myerson, Allan S.,

Journal:

Crystal Growth & Design

Année:

2014

Langue:

english

Fichier:

PDF, 2.92 MB

english, 2014

2

Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study

Schaber, Spencer D., Gerogiorgis, Dimitrios I., Ramachandran, Rohit, Evans, James M. B., Barton, Paul I., Trout, Bernhardt L.

Journal:

Industrial & Engineering Chemistry Research

Année:

2011

Langue:

english

Fichier:

PDF, 1014 KB

english, 2011

3

Continuous Crystallization of Aliskiren Hemifumarate

Quon, Justin L., Zhang, Haitao, Alvarez, Alejandro, Evans, James, Myerson, Allan S., Trout, Bernhardt L.

Journal:

Crystal Growth & Design

Année:

2012

Langue:

english

Fichier:

PDF, 3.03 MB

english, 2012

4

Development of Continuous Crystallization Processes Using a Single-Stage Mixed-Suspension, Mixed-Product Removal Crystallizer with Recycle

Wong, Shin Yee, Tatusko, Adam P., Trout, Bernhardt L., Myerson, Allan S.

Journal:

Crystal Growth & Design

Année:

2012

Langue:

english

Fichier:

PDF, 2.30 MB

english, 2012

5

Regulatory Perspectives on Continuous Pharmaceutical Manufacturing: Moving from Theory to Practice September 26-27, 2016, International Symposium on the Continuous Manufacturing of Pharmaceuticals

Nasr, Moheb M., Krumme, Markus, Matsuda, Yoshihiro, Trout, Bernhardt L., Badman, Clive, Mascia, Salvatore, Cooney, Charles L., Jensen, Keith D., Florence, Alastair, Johnston, Craig, Konstantinov, Kons

Journal:

Journal of Pharmaceutical Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 458 KB

english, 2017

6

Achieving Continuous Manufacturing in Lyophilization: Technologies and Approaches

Pisano, Roberto, Arsiccio, Andrea, Capozzi, Luigi C., Trout, Bernhardt L.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Année:

2019

Langue:

english

Fichier:

PDF, 128 KB

english, 2019

7

Why We Need Continuous Pharmaceutical Manufacturing and How to Make It Happen

Badman, Clive, Cooney, Charles L., Florence, Alastair, Konstantinov, Konstantin, Krumme, Markus, Mascia, Salvatore, Nasr, Moheb, Trout, Bernhardt L.

Journal:

Journal of Pharmaceutical Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 158 KB

english, 2019

8

A screening tool for therapeutic monoclonal antibodies: Identifying the most stable protein and its best formulation based on thioflavin T binding

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Bernhard Helk, Kurt Forrer, Prof. Bernhardt L. Trout

Journal:

Biotechnology Journal

Année:

2012

Langue:

english

Fichier:

PDF, 239 KB

english, 2012

9

Aggregation in protein-based biotherapeutics: Computational studies and tools to identify aggregation-prone regions

Neeraj J. Agrawal, Sandeep Kumar, Xiaoling Wang, Bernhard Helk, Satish K. Singh, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 375 KB

english, 2011

10

Developability index: A rapid in silico tool for the screening of antibody aggregation propensity

Timothy M. Lauer, Neeraj J. Agrawal, Naresh Chennamsetty, Kamal Egodage, Bernhard Helk, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 500 KB

english, 2012

11

Production and characterization of carbamazepine nanocrystals by electrospraying for continuous pharmaceutical manufacturing

Mao Wang, Gregory C. Rutledge, Allan S. Myerson, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 686 KB

english, 2012

12

Effects of Excipients on the Hydrogen Peroxide-Induced Oxidation of Methionine Residues in Granulocyte Colony-Stimulating Factor

Jin Yin, Jhih-Wei Chu, Margaret Speed Ricci, David N. Brems, Daniel I. C. Wang, Bernhardt L. Trout

Journal:

Pharmaceutical Research

Année:

2005

Langue:

english

Fichier:

PDF, 223 KB

english, 2005

13

A consistent and verifiable macroscopic model for the dissolution of liquid CO2 in water under hydrate forming conditions

Ravi Radhakrishnan, Alexander Demurov, Howard Herzog, Bernhardt L Trout

Journal:

Energy Conversion and Management

Année:

2003

Langue:

english

Fichier:

PDF, 156 KB

english, 2003

14

Aggregation-Prone Motifs in Human Immunoglobulin G

Naresh Chennamsetty, Bernhard Helk, Vladimir Voynov, Veysel Kayser, Bernhardt L. Trout

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2009

15

Role of Arginine in the Stabilization of Proteins against Aggregation †

Baynes, Brian M., Wang, Daniel I. C., Trout, Bernhardt L.

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 167 KB

english, 2005

16

Effect of Particle Size on the Adsorption of O and S Atoms on Pt: A Density-Functional Theory Study

Lin, Xi, Ramer, Nicholas J., Rappe, Andrew M., Hass, Kenneth C., Schneider, William F., Trout, Bernhardt L.

Journal:

Journal of Physical Chemistry B

Année:

2001

Langue:

english

Fichier:

PDF, 153 KB

english, 2001

17

Surface Design for Controlled Crystallization: The Role of Surface Chemistry and Nanoscale Pores in Heterogeneous Nucleation

Diao, Ying, Myerson, Allan S., Hatton, T. Alan, Trout, Bernhardt L.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.90 MB

english, 2011

18

Mathematical modeling and design of layer crystallization in a concentric annulus with and without recirculation

Zhou, Lifang, Su, Min, Benyahia, Brahim, Singh, Aniruddh, Barton, Paul I., Trout, Bernhardt L., Myerson, Allan S., Braatz, Richard D.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2013

19

Use of Continuous MSMPR Crystallization with Integrated Nanofiltration Membrane Recycle for Enhanced Yield and Purity in API Crystallization

Ferguson, Steven, Ortner, Franziska, Quon, Justin, Peeva, Ludmila, Livingston, Andrew, Trout, Bernhardt L., Myerson, Allan S.

Journal:

Crystal Growth & Design

Année:

2014

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2014

20

Development of Continuous Anti-Solvent/Cooling Crystallization Process using Cascaded Mixed Suspension, Mixed Product Removal Crystallizers

Zhang, Haitao, Quon, Justin, Alvarez, Alejandro J., Evans, James, Myerson, Allan S., Trout, Bernhardt

Journal:

Organic Process Research & Development

Année:

2012

Langue:

english

Fichier:

PDF, 4.61 MB

english, 2012

21

Polymorphic control by heterogeneous nucleation - A new method for selecting crystalline substrates

Chadwick, Keith, Myerson, Allan, Trout, Bernhardt

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 174 KB

english, 2011

22

Phase diagram of oxygen adsorbed on platinum (111) by first-principles investigation

Tang, Hairong, Van der Ven, Anton, Trout, Bernhardt L.

Journal:

Physical Review B

Année:

2004

Langue:

english

Fichier:

PDF, 534 KB

english, 2004

23

Rational Design of Biobetters with Enhanced Stability

Courtois, Fabienne, Schneider, Curtiss P., Agrawal, Neeraj J., Trout, Bernhardt L.

Journal:

Journal of Pharmaceutical Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 516 KB

english, 2015

24

Achieving Continuous Manufacturing May 20–21 2014 Continuous Manufacturing Symposium

Badman, Clive, Trout, Bernhardt L.

Journal:

Journal of Pharmaceutical Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 44 KB

english, 2015

25

Continuous Crystallization of Cyclosporine: Effect of Operating Conditions on Yield and Purity

Li, Jicong, Lai, Tsai-ta C., Trout, Bernhardt L., Myerson, Allan S.

Journal:

Crystal Growth & Design

Année:

2017

Langue:

english

Fichier:

PDF, 880 KB

english, 2017

26

Development of Maltodextrin Based Immediate Release Tablets using an Integrated Twin-Screw Hot Melt Extrusion and Injection Molding Continuous Manufacturing Process

Puri, Vibha, Brancazio, Dave, Desai, Parind M., Jensen, Keith D., Chun, Jung-Hoon, Myerson, Allan S., Trout, Bernhardt L.

Journal:

Journal of Pharmaceutical Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 677 KB

english, 2017

27

Integrated hot-melt extrusion − injection molding continuous tablet manufacturing platform: Effects of critical process parameters and formulation attributes on product robustness and dimensional stability.

Desai, Parind M., Hogan, Rachael C., Brancazio, David, Puri, Vibha, Jensen, Keith D., Chun, Jung-Hoon, Myerson, Allan S., Trout, Bernhardt L.

Journal:

International Journal of Pharmaceutics

Année:

2017

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2017

28

From batch to continuous: freeze-drying of suspended vials for pharmaceuticals in unit-doses

Capozzi, Luigi Carlo Carlo, Trout, Bernhardt L, Pisano, Roberto

Journal:

Industrial & Engineering Chemistry Research

Année:

2019

Langue:

english

Fichier:

PDF, 7.47 MB

english, 2019

29

Understanding the Role of Preferential Exclusion of Sugars and Polyols from Native State IgG1 Monoclonal Antibodies and its Effect on Aggregation and Reversible Self-Association

Sudrik, Chaitanya M., Cloutier, Theresa, Mody, Neil, Sathish, Hasige A., Trout, Bernhardt L.

Journal:

Pharmaceutical Research

Année:

2019

Langue:

english

Fichier:

PDF, 3.04 MB

english, 2019

30

Molecular computations of preferential interaction coefficients of IgG1 monoclonal antibodies with sorbitol, sucrose, and trehalose and the impact of these excipients on aggregation and viscosity

Cloutier, Theresa, Sudrik, Chaitanya, Mody, Neil, Sathish, Hasige A., Trout, Bernhardt L

Journal:

Molecular Pharmaceutics

Année:

2019

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2019

31

Molecular computations of preferential interaction coefficients of IgG1 monoclonal antibodies with sorbitol, sucrose, and trehalose and the impact of these excipients on aggregation and viscosity

Cloutier, Theresa, Sudrik, Chaitanya, Mody, Neil, Sathish, Hasige A., Trout, Bernhardt L

Journal:

Molecular Pharmaceutics

Année:

2019

Fichier:

PDF, 1.83 MB

2019

32

A comprehensive picture of non-site specific oxidation of methionine residues by peroxides in protein pharmaceuticals

Jhih-Wei Chu, Jin Yin, Bernard R. Brooks, Daniel I.C. Wang, Margaret Speed Ricci, David N. Brems, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 161 KB

english, 2004

33

Evaluation of a non-arrhenius model for therapeutic monoclonal antibody aggregation

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Bernhard Helk, Kurt Forrer, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 720 KB

english, 2011

34

Solid-state NMR characterization of high-loading solid solutions of API and excipients formed by electrospinning

Blair Brettmann, Erin Bell, Allan Myerson, Bernhardt Trout

Journal:

Journal of Pharmaceutical Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 276 KB

english, 2012

35

Application of transition path sampling methods in catalysis: A new mechanism for bond formation in the methanol coupling reaction in chabazite

Cynthia S. Lo, Ravi Radhakrishnan, Bernhardt L. Trout

Journal:

Catalysis Today

Année:

2005

Langue:

english

Fichier:

PDF, 778 KB

english, 2005

36

Diffusion and reaction in ZSM-5 studied by dynamic Monte Carlo

Bernhardt L. Trout, Arup K. Chakraborty, Alexis T. Bell

Journal:

Chemical Engineering Science

Année:

1997

Langue:

english

Fichier:

PDF, 795 KB

english, 1997

37

The interaction of HCl with the (0 0 0 1) face of hexagonal ice studied theoretically via Car–Parrinello molecular dynamics

Yves A. Mantz, Franz M. Geiger, Luisa T. Molina, Mario J. Molina, Bernhardt L. Trout

Journal:

Chemical Physics Letters

Année:

2001

Langue:

english

Fichier:

PDF, 340 KB

english, 2001

38

The dissociation mechanism of H2O in water studied by first-principles molecular dynamics

Bernhardt L Trout, Michele Parrinello

Journal:

Chemical Physics Letters

Année:

1998

Langue:

english

Fichier:

PDF, 85 KB

english, 1998

39

A method to extract potentials from the temperature dependence of Langmuir constants for clathrate-hydrates

Martin Z. Bazant, Bernhardt L. Trout

Journal:

Physica A: Statistical Mechanics and its Applications

Année:

2001

Langue:

english

Fichier:

PDF, 280 KB

english, 2001

40

Prediction of protein binding regions

Naresh Chennamsetty, Vladimir Voynov, Veysel Kayser, Bernhard Helk, Bernhardt L. Trout

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2011

Langue:

english

Fichier:

PDF, 746 KB

english, 2011

41

Tryptophan-Tryptophan Energy Transfer and Classification of Tryptophan Residues in Proteins Using a Therapeutic Monoclonal Antibody as a Model

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Bernhard Helk, Bernhardt L. Trout

Journal:

Journal of Fluorescence

Année:

2011

Langue:

english

Fichier:

PDF, 717 KB

english, 2011

42

Effects of Antioxidants on the Hydrogen Peroxide-Mediated Oxidation of Methionine Residues in Granulocyte Colony-Stimulating Factor and Human Parathyroid Hormone Fragment 13-34

Jin Yin, Jhih-Wei Chu, Margaret Speed Ricci, David N. Brems, Daniel I. C. Wang, Bernhardt L. Trout

Journal:

Pharmaceutical Research

Année:

2004

Langue:

english

Fichier:

PDF, 137 KB

english, 2004

43

Glycosylation influences on the aggregation propensity of therapeutic monoclonal antibodies

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Kurt Forrer, Bernhard Helk, Professor Bernhardt L. Trout

Journal:

Biotechnology Journal

Année:

2011

Langue:

english

Fichier:

PDF, 718 KB

english, 2011

44

Mechanisms of Protein Stabilization and Prevention of Protein Aggregation by Glycerol

Vagenende, Vincent, Yap, Miranda G. S., Trout, Bernhardt L.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 3.21 MB

english, 2009

45

A general set of order parameters for molecular crystals

Santiso, Erik E., Trout, Bernhardt L.

Journal:

The Journal of Chemical Physics

Année:

2011

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2011

46

Solid-state nuclear magnetic resonance study of the physical stability of electrospun drug and polymer solid solutions

Blair Kathryn Brettmann, Allan S. Myerson, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 368 KB

english, 2012

47

Molecular level insight into intra-solvent interaction effects on protein stability and aggregation

Diwakar Shukla, Curtiss P. Schneider, Bernhardt L. Trout

Journal:

Advanced Drug Delivery Reviews

Année:

2011

Langue:

english

Fichier:

PDF, 655 KB

english, 2011

48

Density-functional theory characterization of acid sites in chabazite

Cynthia Lo, Bernhardt L. Trout

Journal:

Journal of Catalysis

Année:

2004

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2004

49

Free Energy of Binding of a Small Molecule to an Amorphous Polymer in a Solvent

Chunsrivirot, Surasak, Trout, Bernhardt L.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 6.34 MB

english, 2011

50

Complex Interactions between Molecular Ions in Solution and Their Effect on Protein Stability

Shukla, Diwakar, Schneider, Curtiss P., Trout, Bernhardt L.

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 838 KB

english, 2011